Cells step back in time

Cells step back in time

Models based on the crystal structure of interleukin-1 vary significantly. D eP ri st o/ El se vi er UK) warns that, for any given structure in the Protein Data Bank (PDB), there will be many other overlooked structures that are equally consistent with the data. Crystallized proteins retain the ability to move around, thus making interpretations of diffraction data an imprecise process. Crystal...

One step forwards, one step back.

Religiosity and telomere length: One step forward, one step back.

a Harvard T.H. Chan School of Public Health, Department of Epidemiology, Program on Integrative Knowledge and Human Flourishing, Harvard University, National Consortium on Psychosocial Stress, Spirituality, and Health, United States b Harvard Medical School, Harvard/MGH Center on Genomics, Vulnerable Populations, and Health Disparities, National Consortium on Psychosocial Stress, Spirituality, ...

The Next Step Forward Is to Take a Step Back.

Understanding the causes of diabetes is at the heart of most diabetes research. The field of causal inference has made dramatic advances in methodology that allows for causal inference from observational and not experimental data (1). One such methodological advancement is the use of genetic markers as instrumental variables, or so-called Mendelian randomization (MR) (2). MR relies on the laws ...

A new predictive formula for calculation of equilibrium pH: a step back in time.

TO THE EDITOR: Nguyen et al. (4) report “the first quantitative approach that can predict the equilibrium [H ] based on the partitioning of H buffering among the different buffer pairs in solution.” To claim no previous method could calculate final equilibrium concentrations from starting preequilibrium concentrations is incorrect, since the ability to perform such calculations was achieved ove...